Myths and facts about bone marrow donation Learn the truth behind common false beliefs about donation. FACT: Donating is less painful than you probably think. While TV shows and movies have wildly exaggerated blood stem cell donation—especially bone marrow donation—as something scary, the reality is much less dramatic.
Discomfort during recovery varies from person to person. Side effects may include back pain, fatigue, headache or bruising for a few days or weeks. The vast majority of donors say it was worth it to help save a life, and they would do it again. Linda, marrow donor FACT: Most blood stem cell donors give peripheral blood stem cells—a process similar to donating plasma. PBSC donation is a nonsurgical procedure and the most common way to donate.
For 5 days leading up to donation, you will be given injections of a drug called filgrastim to increase the number of cells in your bloodstream that are used for transplant. Some of your blood is then removed through a needle in one arm and passed through a machine that separates out the blood-forming cells. The remaining blood is returned to you through the other arm.
PBSC Preparation. You will receive daily injections of filgrastim for 5 days leading up to the donation procedure. Filgrastim is a protein similar to a hormone naturally produced in the body. Filgrastim moves the blood-forming cells out of your marrow and into your bloodstream so that there are enough blood-forming cells for a transplant. The injections of filgrastim may be given to you by a home health nurse, or a nurse or doctor at a local clinic, or a donor center staff member.
After you receive the injections, and until you donate, you may experience side effects including headache, bone or muscle pain, nausea, difficulty sleeping, tiredness, or decrease in blood platelet count. PBSC donation may require placement of a central line if you do not have suitable arm veins. A central venous line is a sterile tube that is inserted into one of the larger veins — the femoral vein in your upper thigh, internal jugular vein in your neck or subclavian vein in your chest.
The risk of serious complications from use of a central line is small. A central line will be placed only with your consent after you have received information about the possible risks. The effects of the injections that increased the blood-forming cells in your bloodstream will go away shortly after the procedure, usually in a few days. Under this protocol, the NMDP is monitoring the effects of the donor's experience while receiving filgrastim.
The first must be given at a donor center or medical clinic, and the fifth will be given at the location where you will undergo the donation procedure. The injections on days two through four may be given at your place of work, your home, at the donor center or a medical clinic. If your recipient's transplant center is in the U. However, each country has different rules about giving updates.
If your recipient is at a transplant center in another country, you may never receive an update or updates on your recipient. During the first year after transplant, some centers allow anonymous communication between you and your recipient. Some centers allow direct contact between donors and recipients one or more years after the transplant, if both you and your recipient consent.
Some centers do not allow you to have contact with your recipient at any time. While transplantation is a life-saving therapy, not all recipients survive. Sometimes a patient's body cannot withstand the pre-transplant chemotherapy and radiation. Sometimes health complications occur after the transplant. But for many recipients, a transplant is successful and their best or only option. Your gift gives them hope and a second chance at life.
Donation FAQs Need help deciding if donating bone marrow is right for you? How is a bone marrow match determined? How likely is it that I will match a patient and go on to donate? What happens if I match a patient? Can I change my mind? How are bone marrow and peripheral blood stem cell PBSC donation different? Who pays for the donation process? How long does donating take? What if I have medical complications related to the donation?
What is the bone marrow donation process like? Does donating marrow hurt? Are there side effects? Are there any risks to marrow donation? Will donating marrow make me weak?
Where is the bone marrow donation done? What is PBSC donation? Why is PBSC donation considered investigational? What is the PBSC donation process like? Does donating PBSC hurt? Are there risks to donating PBSC? Where is the PBSC donation done? Will I get patient updates or meet my transplant recipient? The procedure is comparable to giving blood, campaigners say, and the judges who ruled in her favour said it rendered the phrase "bone marrow transplant" obsolete.
But the Obama administration has appealed the ruling. It argues the aphaeresis contravenes federal law banning the sale of human organs - including bone marrow. Jeff Rowes, a lawyer for the Institute for Justice, which represents the Flynn family, says the law is out of date. You can compensate donors of plasma and platelets and there's no reason why you shouldn't be able to compensate bone marrow donors when you get the cells in exactly the same way.
The government challenge is a major setback for the Flynn family, who are running out of time to find a match for year-old Jordan. She's become so sick doctors have only a couple of months left to perform a transplant with the most suitable donor they can find - and even that won't guarantee her survival. Her seven-year-old twin sister's health is also beginning to deteriorate.
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